Therapeutic potential of megadose vitamin C to reverse organ dysfunction in sepsis and COVID-19
Abstract Sepsis induced by bacteria or viruses can result in multiorgan dysfunction, which is a major cause of death in intensive care units. Current treatments are only supportive, and there are no treatments that reverse the pathophysiological effects of sepsis. Vitamin C has antioxidant, anti-inflammatory, anticoagulant and immune modulatory actions, so it is a rational […]
The Relationship between Vitamin C and Periodontal Diseases: A Systematic Review
Abstract Vitamin C is important for preventing and slowing the progression of many diseases. There is significant evidence linking periodontal disease and vitamin C. We aimed to systematically review the studies addressing the relationship between vitamin C and periodontal disease, and the preventive ability of vitamin C against periodontal disease. Electric searches were performed using […]
Sodium ascorbate (vitamin C) induces apoptosis in melanoma cells via the down-regulation of transferrin receptor dependent iron uptake
Abstract Sodium ascorbate (vitamin C) has a reputation for inconsistent effects upon malignant tumor cells, which vary from growth stimulation to apoptosis induction. Melanoma cells were found to be more susceptible to vitamin C toxicity than any other tumor cells. The present study has shown that sodium ascorbate decreases cellular iron uptake by melanoma cells […]
High doses of sodium ascorbate interfere with the expansion of glioblastoma multiforme cells in vitro and in vivo
Aims Constant development of chemotherapeutic strategies has considerably improved the efficiency of tumor treatment. However, adverse effects of chemotherapeutics enforce premature treatment cessation, which leads to the tumor recurrence and accelerated death of oncologic patients. Recently, sodium ascorbate (ASC) has been suggested as a promising drug for the adjunctive chemotherapy of glioblastoma multiforme (GBM) and prostate cancer (PC). To estimate whether ASC can […]
UnCensored Transparen-C
Critical Emergency COVID-19 & Comprehensive Vitamin C Therapy Medical Webinar From the original front lines in China: “Consensus of expert panel from Shanghai, China recommends IV vitamin C in the treatment of the COVID19 virus. Early reports from the principle investigator point to reduced cytokine, inflammatory burst in the COVID19 with the use […]
Pandemic Pathogens & Pandemonium
Schools and workplaces are shut-down for an indefinite period of time, public recreational facilities and beaches are closed during the high season spring-break, cities across the country are under lockdown and mayors and governors across the country continue to implement additional drastic Coronavirus measures and directives in an attempt to thwart the spread of the […]
February Newsletter – Coronavirus Health Crisis
Coronavirus – A Serious Global Health Threat or Treatable Condition? News about the Coronavirus outbreak which started in Wuhan, China, is changing rapidly and the media frenzy has created a colossal public panic causing massive economic consequences and alarmingly rising fear among Americans who are desperate to find a preventative measure for this fast spreading […]